Contract Research and Development

Pre-Formulation Studies

• Rapid screening studies
• Proof of Concept (PoC) studies
• Excipient compatibility studies
  • Solid and Liquid State

Solubility Screening

• Solid Dispersions
• Surfactant and co-solvent screenings
• Analytical characterization of solid dispersions including kinetic solubility and dissolution rate.

Formulation & Process Development

• Identify lead binary polymer / drug formulations
• Characterize and Generate Stability Information
  • Super Saturation and Dissolution rate
  • Drug Assay and Purity
  • DSC & TGA
  • Microscopy
  • SEM, X-ray diffraction, NMR available through partner laboratorie
• 3-10g melt extrusion batches
• 50g and up twin screw extrustion batches (16mm)
• 100g and up twin screw extrusion batches (18 mm)
• 5kg and up twin screw extrusion batches (27 mm) 
• Custom processes specific to your formulation or product include:
  • Drying and Material Handling
  • Feeder Selection
  • Screw design
  • Barrel configuration
  • Die design
  • Tight tolerance extrusion (film, fiber and shapes)
  • Feedback control systems