Melt extrusion can be used as a process for the manufacture of many dosage forms. Foster’s inventory of downstream processing equipment is available to manufacture traditional and customized shapes.
Drug Delivery and Implantable Polymer Pellets:
Foster’s hot melt extruded blends of biocompatible polymers with active pharmaceutical ingredients, bone growth additives and other targeted therapeutic ingredients are available in a wide range of powders, micro-pellets and traditional pellets. Common micro-pellet sizes range from 0.029 to 0.047 inches (0.5 to 1.2 millimeters). Traditional pellets are typically 0.059 to 0.118 inches (1.5 to 3.0 millimeters).
Drug Delivery and Implantable Polymer Fibers:
Monofilament fibers for drug delivery and implantable applications are available with diameters ranging from 0.012 to 0.028 inches (0.30 to 0.7 millimeters) for implants, woven structures and more. Fiber tensile properties vary depending on the polymer and application requirements.
Drug Delivery and Implantable Polymer Films:
Films used for drug delivery and implantable applications are available in sizes ranging up to 5.25 inches (133.4 millimeters) wide and thicknesses of 0.0012 to 0.0394 inches (0.03 to 1.00 millimeters). Drug eluting films are used for localized delivery in applications such as post-operative therapy wraps. Fast dissolving drug delivery films are used for transdermal, transmucosal and buccal patches.
Drug Delivery and Implantable Polymer Tubes:
Implantable and drug delivery tubes can be made from a wide range of biocompatible polymers to meet specific application requirements. Single lumen, single materials are most common for implants with diameters as small as 0.0098 inches (0.25 millimeters) with wall thicknesses as small as 0.0004 inches (0.01 millimeters).