A significant number of new active pharmaceutical ingredients (APIs) are poorly water soluble and cannot be formulated and processed with traditional aqueous methods. Hot melt extrusion (HME) has become an effective solubilization tool in improving the dissolution rate of poorly water soluble drugs to enhance their bioavailability after oral administration1. These crystalline hydrophobic drugs can be dispersed in hydrophilic polymers using HME to manufacture amorphous solid dispersions.
News & Events
Foster Delivery Science is a sponsor at the 6th Drug Formulation, Solubility & Bioavailability Summit held at the Hilton Back Bay in Boston March 27-29th!
Tony Listro, VP of Foster Delivery Science has been featured in the March/April issue of Orthopedic Design & Technology.